FBXW11 ELISA kits are immunoassay tools for the measurement of the protein F-box and WD repeat domain containing 11, which is encoded by the FBXW11 gene in humans. Functionally, this protein is reported to be a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The canonical protein structure is reported to have an amino acid sequence of 542 residues and a mass of 62.1 kDa. It is known to be localized in the nucleus and cytoplasm. As many as 3 protein isoforms have been reported. The FBXW11 gene has been associated with the disease, Neurodevelopmental, jaw, eye, and digital syndrome. Other alias names for this target include BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, NEDJED, F-box/WD repeat-containing protein 11, and BTRC2.
Some FBXW11 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.