IBTK ELISA kits are immunoassay tools for the measurement of the protein inhibitor of Bruton tyrosine kinase, which is encoded by the IBTK gene in humans. Functionally, this protein is known to act as a inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. The canonical protein structure is reported to have an amino acid sequence of 1353 residues and a mass of 150.5 kDa. It is known to be localized in the membrane and cytoplasm and is reported to be expressed in DeFew, HEK293T, HeLa and in Jurkat, MC3 and NB4 lymphoid cells. As many as 3 protein isoforms have been reported. Other alias names for this target include BTKI, BTK-binding protein, Bruton agammaglobulinemia tyrosine kinase inhibitor, inhibitor of Bruton's tyrosine kinase-alpha, and BTBD26.
Some IBTK ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.