GAD1 ELISA kits are immunoassay tools for the measurement of the protein glutamate decarboxylase 1, which is encoded by the GAD1 gene in humans. Functionally, this protein is known to catalyze the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. The canonical protein structure is reported to have an amino acid length of 594 residues, a mass of 66.9 kDa, and is a member of the Group II decarboxylase protein family. As many as 4 protein isoforms have been reported. The GAD1 gene has been associated with the disease, Developmental and epileptic encephalopathy. Other alias names for this target include DEE89, GAD, SCP, 67 kDa glutamic acid decarboxylase, GAD-67, glutamate decarboxylase 1 (brain, 67kDa), and CPSQ1.
The detection range for different GAD1 ELISA kits can vary, with some assays measuring target concentrations as low as 3 ng/L and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.