XBP1 ELISA kits are immunoassay tools for the measurement of the protein X-box binding protein 1, which is encoded by the XBP1 gene in humans. Functionally, this protein is known to function as a transcription factor during endoplasmic reticulum (ER) stress by regulating the unfolded protein response (UPR). The canonical protein structure is reported to have an amino acid length of 261 residues, a mass of 28.7 kDa, and is a member of the BZIP protein family. It is known to be localized in the ER and is reported to be expressed in plasma cells in rheumatoid synovium. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated, acetylated and cleaved. The XBP1 gene has been associated with the disease, Major affective disorder. Other alias names for this target include TREB5, XBP2, tax-responsive element-binding protein 5, and TREB-5.
Some XBP1 ELISA kits can detect targets at levels as low as 3 ng/L and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.