OCRL ELISA kits are immunoassay tools for the measurement of the protein OCRL inositol polyphosphate-5-phosphatase, which is encoded by the OCRL gene in humans. Functionally, this protein is known to catalyze the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2. The canonical protein structure is reported to have an amino acid length of 901 residues, a mass of 104.2 kDa, and is a member of the Inositol 1,4,5-trisphosphate 5-phosphatase type II protein family. It is known to be localized in the cytoplasm. As many as 2 protein isoforms have been reported. The OCRL gene has been associated with the disease, Lowe oculocerebrorenal syndrome. Other alias names for this target include Dent-2, INPP5F, LOCR, NPHL2, OCRL-1, OCRL1, inositol polyphosphate 5-phosphatase OCRL, and DENT2.
There are OCRL ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.