The following OCCLUDIN ELISA kits are useful research tools for the measurement of occludin in biological samples. In humans this protein is encoded by the OCLN gene. This protein is believed to play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. The canonical protein structure is reported to have an amino acid length of 522 residues, a mass of 59.1 kDa, and is a member of the ELL/occludin protein family. Its subcellular location is known to be in the cell membrane. As many as 7 protein isoforms have been reported. In certain instances, it is also post-translationally cleaved and phosphorylated. The gene encoding this protein has been associated with the disease, Pseudo-TORCH syndrome. This protein may also be known as phosphatase 1, regulatory subunit 115.
The detection range for different occludin ELISA kits can vary, with some assays measuring target concentrations as low as 5 ng/L and as high as 150 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.