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Recent Product Review

  • 1uL CD8-V450 Work Great To Detect CD8+ T Cells

    1uL CD8-V450 Work Great To Detect CD8+ T Cells

    Our group studies T cells in the blood of untreated chronic HIV+ individuals. We are constantly expanding and optimizing our T cell panels to measure various T cell subsets, activation, and inhibitory receptor phenotype. We use CD8-V450 in a few of our T cell panels because the staining looks great and it is cost-efficient.
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    Our laboratory investigates different ways to improve immune responses against HIV, including enhancement of the capacity of effector cells, such as NK cells, to kill HIV-infected cell. We are currently investigating the capacity of an engineered antibody to trigger NK-cell mediated ADCC activity in in vitro assays against an HIV-infected cell line, ACH2, which expresses high levels of human CD5. We perform FACS-based killing assays, where we use human CD5 as a marker to distinguish the target cells.

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