ABCA3 ELISA kits are immunoassay tools for the measurement of the protein ATP binding cassette subfamily A member 3, which is encoded by the ABCA3 gene in humans. Functionally, this protein is known to catalyze the ATP-dependent transport of phospholipids such as phosphatidylcholine and phosphoglycerol from the cytoplasm into the lumen side of lamellar bodies, in turn participates in the lamellar bodies biogenesis and homeostasis of pulmonary surfactant. The canonical protein structure is reported to have an amino acid length of 1704 residues, a mass of 191.4 kDa, and is a member of the ABCA protein family. It is known to be localized in the cytoplasmic vesicles and lysosomes and is reported to be expressed in the brain, pancreas, skeletal muscle and heart. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated and cleaved. The ABCA3 gene has been associated with the disease, Pulmonary surfactant metabolism dysfunction. Other alias names for this target include ABC3, EST111653, LBM180, SMDP3, phospholipid-transporting ATPase ABCA3, and ABC-C.
Some ABCA3 ELISA kits can detect targets at levels as low as 20 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.