Anti-GRIPE antibodies enable researchers to detect and measure the GRIPE antigen in biological samples. This target is a reported synonym of the RALGAPA1 gene, which encodes Ral GTPase activating protein catalytic subunit alpha 1. This protein is known to function in GTPase activation and GPCR signaling pathways, among other biological roles. The human version of GRIPE has a canonical amino acid length of 2036 residues and a protein mass of 229.8 kilodaltons, although 7 isoforms have been identified. It is reported to be localized in the nucleus and cytoplasm of cells and notably expressed in many tissues, such as the caudate, testis, and adrenal gland.