Anti-Comt2 antibodies enable researchers to detect and measure the Comt2 antigen in biological samples. This target is a reported synonym of the TOMT gene, which encodes transmembrane O-methyltransferase. This protein is known to function in metabolic processes, among other biological roles. The human version of Comt2 has a canonical amino acid length of 291 residues and a protein mass of 32.2 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the ER and cytoplasm of cells. Comt2 is a member of the Cation-dependent O-methyltransferase protein family.