Anti-CIA-II antibodies enable researchers to detect and measure the CIA-II antigen in biological samples. This target is a reported synonym of the ASF1B gene, which encodes anti-silencing function 1B histone chaperone. This protein is known to function in cell differentiation and DNA replication, among other biological roles. The human version of CIA-II has a canonical amino acid length of 202 residues and a protein mass of 22.4 kilodaltons. It is reported to be localized in the nucleus and cytoplasm of cells and notably expressed in the small intestine, oral mucosa, epididymis, duodenum, and cerebral cortex. CIA-II is a member of the ASF1 protein family.