Anti-JAM-B antibodies enable researchers to detect and measure the JAM-B antigen in biological samples. This target is a reported synonym of the JAM2 gene, which encodes junctional adhesion molecule 2. This protein is known to function in cell adhesion and spermatid development, among other biological roles. The human version of JAM-B has a canonical amino acid length of 298 residues and a protein mass of 33.2 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the cell membrane of cells. JAM-B is a member of the Immunoglobulin protein superfamily.