Anti-LRRC8D antibodies are used in the immunodetection of the protein leucine rich repeat containing 8 VRAC subunit D. In humans, the canonical protein has a reported length of 858 amino acid residues and a mass of 98.2 kDa. Its subcellular localization is in the ER and cell membrane. A member of the LRRC8 protein family, LRRC8D is reported to be a non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. Synonyms for this target antigen include LRRC5, volume-regulated anion channel subunit LRRC8D, leucine rich repeat containing 5, leucine rich repeat containing 8 family member D, and HsLRRC8D. LRRC8D gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some LRRC8D antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.