Anti-alpha-L-iduronidase antibodies are used for the immunodetection of the protein encoded by the IDUA gene. In humans, the canonical protein has a reported length of 653 amino acid residues and a mass of 72.7 kDa. Its subcellular localization is in the lysosomes. Alternative splicing is reported to yield 2 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of the Glycosyl hydrolase 39 protein family, it is known to be involved with metabolic processes. Post-translational modifications have been described, including N-glycosylation. Other names for this target antigen include MPS1, MPSI, iduronidase alpha-L-, mucopolysaccharidosis type I, and IDA. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of alpha-L-iduronidase antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.