Anti-Janus kinase 1 antibodies are used for the immunodetection of the protein encoded by the JAK1 gene. In humans, the canonical protein has a reported length of 1154 amino acid residues and a mass of 133.3 kDa. Its subcellular localization is in the membrane. It is noted to be expressed at higher levels in primary colon tumors than in normal colon tissue. A member of the Tyr protein kinase protein family, it is known to be involved with cell differentiation and viral immune response. Post-translational modifications have been described, including ubiquitination and phosphorylation. Other names for this target antigen include JAK1A, JAK1B, JTK3, tyrosine-protein kinase JAK1, and AIIDE. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 570 citations in the literature describe the use of Janus kinase 1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.