Anti-Neuronal pentraxin 1 antibodies are used in the immunodetection of the protein encoded by the NPTX1 gene. In humans, the canonical protein has a reported length of 432 amino acid residues and a mass of 47.1 kDa. Its subcellular localization is in the cytoplasmic vesicles. It is suspected to be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include SCA50, NP-I, neuronal pentraxin I, and NP1.