Anti-Neurogranin antibodies are used in the immunodetection of the protein encoded by the NRGN gene. In humans, the canonical protein has a reported length of 78 amino acid residues and a mass of 7.6 kDa. A member of the Neurogranin protein family, it is known to act as a 'third messenger' substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include hng, calmodulin-binding protein, neurogranin (protein kinase C substrate, RC3), protein kinase C substrate, and RC3.