Anti-ATP8B3 antibodies are used in the immunodetection of the protein ATPase phospholipid transporting 8B3. In humans, the canonical protein has a reported length of 1300 amino acid residues and a mass of 146.8 kDa. Its subcellular localization is in the cytoplasmic vesicles and ER. Up to 3 different isoforms have been reported for this protein. A member of the Cation transport ATPase (P-type) (TC 3.A.3) protein family, ATP8B3 is reported to be a P4-ATPase flippase, which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Synonyms for this target antigen include ATPase, aminophospholipid transporter, class I, type 8B, member 3, ATPase, class I, type 8B, member 3, aminophospholipid translocase ATP8B3, and phospholipid-transporting ATPase IK. ATP8B3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Western Blot is a widely used application for the ATP8B3 antibodies listed below. In addition, ELISA is also a common application.