Anti-TMEM39B antibodies are used in the immunodetection of the protein transmembrane protein 39B. In humans, the canonical protein has a reported length of 492 amino acid residues and a mass of 56.3 kDa. Its subcellular localization is in the ER. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the TMEM39 protein family, TMEM39B is believed to protect the cells against DNA damage caused by exposure to the cold-warming stress and facilitates tissue damage repair during the recovery phase. Post-translational modifications have been described, including glycosylation. TMEM39B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. These TMEM39B antibodies are widely used in Western Blot experiments, among other applications.