Anti-nuclear cap binding protein subunit 1, 80kDa antibodies are used in antigen-specific immunodetection in biological samples. The target nuclear cap binding protein subunit 1, 80kDa is a known alias name of the protein nuclear cap binding protein subunit 1, encoded by the NCBP1 gene in humans. This 790-amino acid residue protein is a known component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. It is localized to the nucleus and cytoplasm of the cell. It is reported to be widely expressed in many tissue types. Other synonyms for nuclear cap binding protein subunit 1, 80kDa include CBP80, NCBP, and Sto1.