Anti-ADAMTS3 Antibody Products

Anti-ADAMTS3 antibodies are used in the immunodetection of the protein ADAM metallopeptidase with thrombospondin type 1 motif 3. In humans, the canonical protein has a reported length of 1205 amino acid residues and a mass of 135.6 kDa. Its subcellular localization is in the extracellular matrix and is secreted. ADAMTS3 is known to be involved with extracellular matrix organization and in utero embryonic development. Post-translational modifications have been described, including N-glycosylation and protein cleavage.

The ADAMTS3 marker can be used to identify Deep-Layer Intratelencephalic Neurons and Eccentric Medium Spiny Neurons.* Synonyms for this target antigen include HKLLS3, A disintegrin and metalloproteinase with thrombospondin motifs 3, PC II-NP, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3, and ADAMTS-4. ADAMTS3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. ELISA, Western Blot, and Immunohistochemistry are common applications for ADAMTS3 antibodies.