Anti-PADI4 antibodies are used in the immunodetection of the protein peptidyl arginine deiminase 4. In humans, the canonical protein has a reported length of 663 amino acid residues and a mass of 74.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is reported to be expressed in eosinophils and neutrophils, not expressed in peripheral monocytes or lymphocytes. A member of the Protein arginine deiminase protein family, PADI4 is known to catalyze the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. Synonyms for this target antigen include PAD4, PADI5, PDI4, PDI5, protein-arginine deiminase type-4, HL-60 PAD, PADI-H protein, and PAD. PADI4 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Over 100 citations in the literature describe the use of PADI4 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.