Anti-CRHR1 antibodies are used in the immunodetection of the protein corticotropin releasing hormone receptor 1. In humans, the canonical protein has a reported length of 444 amino acid residues and a mass of 50.7 kDa. Its subcellular localization is in the cell membrane. Up to 5 different isoforms have been reported for this protein. It is reported to be highly expressed in the the cerebellum, pituitary, cerebral cortex and olfactory lobe. A member of the G-protein coupled receptor 2 protein family, CRHR1 is known to be involved with GPCR signaling pathways and receptor-mediated signaling pathways. Synonyms for this target antigen include CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRHR, CRHR1L, and CRF-R. CRHR1 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Over 50 citations in the literature describe the use of CRHR1 antibodies in research. Immunohistochemistry is a widely used application for these antibodies. Western Blot and Immunofluorescence are also common applications.