Anti-TNFRSF11B antibodies are used in the immunodetection of the protein TNF receptor superfamily member 11b. In humans, the canonical protein has a reported length of 401 amino acid residues and a mass of 46 kDa. It has been described to be a secreted protein. It is reported to be highly expressed in adult lung, heart, kidney, liver, spleen, thymus, prostate, ovary, small intestine, thyroid, lymph node, trachea, adrenal gland, testis, and bone marrow. TNFRSF11B is known to act as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Synonyms for this target antigen include OPG, PDB5, TR1, tumor necrosis factor receptor superfamily member 11B, osteoclastogenesis inhibitory factor, and OCIF. TNFRSF11B gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 260 citations in the literature describe the use of TNFRSF11B antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.