Anti-CACNG5 antibodies are used in the immunodetection of the protein calcium voltage-gated channel auxiliary subunit gamma 5. In humans, the canonical protein has a reported length of 275 amino acid residues and a mass of 30.9 kDa. Its subcellular localization is in the membrane. A member of the PMP-22/EMP/MP20 protein family, CACNG5 is reported to regulate the gating properties of AMPA-selective glutamate receptors (AMPARs).
The CACNG5 marker can be used to identify Eccentric Medium Spiny Neurons.* Synonyms for this target antigen include TARP gamma-5, calcium channel, voltage-dependent, gamma subunit 5, neuronal voltage-gated calcium channel gamma-5 subunit, and voltage-dependent calcium channel gamma-5 subunit. CACNG5 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some CACNG5 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4