Anti-NISCH antibodies are used in the immunodetection of the protein nischarin. In humans, the canonical protein has a reported length of 1504 amino acid residues and a mass of 166.6 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. NISCH is known to act either as the functional imidazoline-1 receptor (I1R) candidate or as a membrane-associated mediator of the I1R signaling. Synonyms for this target antigen include IR1, IRAS, hIRAS, I-1 receptor candidate protein, I1R candidate protein, and I-1. NISCH gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of NISCH antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.