Anti-CFL1 antibodies are used in the immunodetection of the protein cofilin 1. In humans, the canonical protein has a reported length of 166 amino acid residues and a mass of 18.5 kDa. It is reported to be widely expressed in various tissues. A member of the Actin-binding proteins ADF protein family, Cfl1 is known to bind to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include HEL-S-15, cofilin, 18 kDa phosphoprotein, cofilin 1 (non-muscle), epididymis secretory protein Li 15, p18, and CFL. CFL1 gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. Over 980 citations in the literature describe the use of Cfl1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.