Anti-SAV1 antibodies are used in the immunodetection of the protein salvador family WW domain containing protein 1. In humans, the canonical protein has a reported length of 383 amino acid residues and a mass of 44.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is widely expressed across many tissue types. SAV1 is a reported regulator of stk3/mst2 and STK4/MST1 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include 1700040G09Rik, 45 kDa WW domain protein, WW domain-containing adaptor 45, hWW45, salvador homolog 1, and protein salvador homolog 1. SAV1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 60 citations in the literature describe the use of SAV1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.