Anti-AGXT antibodies are used in the immunodetection of the protein alanine--glyoxylate aminotransferase. In humans, the canonical protein has a reported length of 392 amino acid residues and a mass of 43 kDa. Its subcellular localization is in the peroxisomes. It is notably expressed in the liver. A member of a the Class-V pyridoxal-phosphate-dependent aminotransferase protein family, AGXT is reported to be a peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification. Synonyms for this target antigen include AGT1, AGXT1, PH1, SPAT, SPT, Ser-PyrAT, TLH6, and AGT.