Anti-HJV antibodies are used in the immunodetection of the protein hemojuvelin BMP co-receptor. In humans, the canonical protein has a reported length of 426 amino acid residues and a mass of 45.1 kDa. Its subcellular localization is in the cell membrane. Up to 3 different isoforms have been reported for this protein. A member of the Repulsive guidance molecule (RGM) protein family, HJV is known to act as a bone morphogenetic protein (BMP) coreceptor. Post-translational modifications have been described, including protein cleavage and glycosylation. The HJV gene has been associated with the disease, Hemochromatosis. Synonyms for this target antigen include RGM domain family member C, haemojuvelin, hemochromatosis type 2 (juvenile), hemochromatosis type 2 protein, repulsive guidance molecule c, and hemojuvelin. HJV gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of HJV antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.