Anti-PR/SET domain 2 antibodies are used for the immunodetection of the protein encoded by the PRDM2 gene. In humans, the canonical protein has a reported length of 1718 amino acid residues and a mass of 188.9 kDa. Its subcellular localization is in the nucleus. It is reported to be highly expressed in retinoblastoma cell lines and in the brain tumors. A member of the Class V-like SAM-binding methyltransferase protein superfamily, it is known to be involved with the regulation of transcription. Other names for this target antigen include KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2, PR domain zinc finger protein 2, and HUMHOXY1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Immunohistochemistry is the most common application for the PR/SET domain 2 antibodies listed below. ELISA and Western Blot are also common applications.