Anti-HIBCH antibodies are used in the immunodetection of the protein 3-hydroxyisobutyryl-CoA hydrolase. In humans, the canonical protein has a reported length of 386 amino acid residues and a mass of 43.5 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the liver and kidney, also detected in the heart, muscle and brain. It is a member of the Enoyl-CoA hydratase/isomerase protein family. Synonyms for this target antigen include 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-Coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H, testicular tissue protein Li 86, and HIBYLCOAH. HIBCH gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some HIBCH antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Flow Cytometry, Immunofluorescence, and Immunohistochemistry are also common applications.