Anti-SELENOS antibodies are used in the immunodetection of the protein selenoprotein S. In humans, the canonical protein has a reported length of 189 amino acid residues and a mass of 21.2 kDa. Its subcellular localization is in the ER and cytoplasm. It is notably widely expressed in many tissue types. A member of the Selenoprotein S protein family, SELENOS is reported to be involved in degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include VCP-interacting membrane protein, tanis, valosin-containing protein-interacting membrane protein, and VCP interacting membrane selenoprotein. SELENOS gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 60 citations in the literature describe the use of SELENOS antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.