Anti-LRRC8A antibodies are used in the immunodetection of the protein leucine rich repeat containing 8 VRAC subunit A. In humans, the canonical protein has a reported length of 810 amino acid residues and a mass of 94.2 kDa. Its subcellular localization is in the lysosomes and cell membrane. It is reported to be expressed in the brain, kidney, ovary, lung, liver, heart, and fetal brain and liver. A member of the LRRC8 protein family, LRRC8A is an important component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. Synonyms for this target antigen include leucine rich repeat containing 8 family member A, leucine-rich repeat-containing protein 8A, swelling protein 1, and volume-regulated anion channel subunit LRRC8A. A number of LRRC8A antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.