Anti-killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 antibodies are used for the immunodetection of the protein encoded by the KIR2DS2 gene. In humans, the canonical protein has a reported length of 304 amino acid residues and a mass of 33.5 kDa. Its subcellular localization is in the cell membrane. A member of the Immunoglobulin protein superfamily, it is a known receptor on natural killer (NK) cells for HLA-C alleles. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include CD158 antigen-like family member J, KIR2DS2 Killer-cell Immunoglobulin-like Receptor, MHC class I NK cell receptor, and killer cell immunoglobulin-like receptor 2DS2. Over 90 citations in the literature describe the use of killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Flow Cytometry are also common applications.