Anti-nuclear factor I X Antibody Products

Anti-nuclear factor I X antibodies are used for the immunodetection of the protein encoded by the NFIX gene. In humans, the canonical protein has a reported length of 502 amino acid residues and a mass of 55.1 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 6 different isoforms for this protein. It is widely expressed across many tissue types. A member of the CTF/NF-I protein family, it is known to recognize and bind the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2.

The nuclear factor I X marker can be used to characterize Ventral Inhibitory Neurons and Medial Excitatory Neurons.* Other names for this target antigen include MALNS, MRSHSS, NF1-X, NF1A, SOTOS2, nuclear factor 1 X-type, CCAAT-box-binding transcription factor, and CTF. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of nuclear factor I X antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.