Anti-APPL2 antibodies are used in the immunodetection of the protein adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. In humans, the canonical protein has a reported length of 664 amino acid residues and a mass of 74.5 kDa. Up to 3 different isoforms have been reported for this protein. It is notably expressed in the brain, heart, kidney and skeletal muscle. APPL2 is known to be involved with the cell cycle and carbohydrate metabolism and homeostasis. Synonyms for this target antigen include DCC-interacting protein 13-beta, DIP13 beta, adapter protein containing PH domain, PTB domain and leucine zipper motif 2, and DIP13B. APPL2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of APPL2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.