Anti-GRIA2 antibodies are used in the immunodetection of the protein glutamate ionotropic receptor AMPA type subunit 2. In humans, the canonical protein has a reported length of 883 amino acid residues and a mass of 98.8 kDa. Its subcellular localization is in the ER and cell membrane. Up to 4 different isoforms have been reported for this protein. It is notably expressed in the hippocampus, cerebral cortex, cerebellum, and caudate. A member of the Glutamate-gated ion channel (TC 1.A.10.1) protein family, GRIA2 is a known receptor for glutamate that functions as ligand-gated ion channel in the central nervous system. Synonyms for this target antigen include GLURB, GluA2, GluR-K2, HBGR2, NEDLIB, gluR-2, gluR-B, and GLUR2. GRIA2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 310 citations in the literature describe the use of GRIA2 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.