Anti-I-TRAF antibodies are used in antigen-specific immunodetection in biological samples. The target I-TRAF is a known alias name of the protein TRAF family member associated NFKB activator, encoded by the TANK gene in humans. This 425-amino acid residue protein is known to be an adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. It is localized to the cytoplasm of the cell and features cleaved and phosphorylated post-translational modifications. In terms of tissue expression, it is ubiquitously expressed across many tissue types. Indicated applications for I-TRAF antibodies listed below include ELISA, Western Blot, and Immunohistochemistry.