Anti-NYX antibodies are used in the immunodetection of the protein nyctalopin. In humans, the canonical protein has a reported length of 481 amino acid residues and a mass of 52 kDa. Its subcellular localization is in the extracellular matrix and is secreted. It is reported to be expressed in the kidney and retina. It is a member of the Small leucine-rich proteoglycan (SLRP) protein family. Post-translational modifications have been described, including glycosylation. The NYX gene has been associated with the disease, Night blindness. Synonyms for this target antigen include leucine-rich repeat protein. NYX gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is a widely used application for the NYX antibodies listed below. In addition, Immunohistochemistry is also a common application.