Anti-Kremen antibodies enable researchers to detect and measure the Kremen antigen in biological samples. This target is a reported synonym of the KREMEN1 gene, which encodes kringle containing transmembrane protein 1. This protein is known to function in the apoptotic pathway and limb development, among other biological roles. The human version of Kremen has a canonical amino acid length of 473 residues and a protein mass of 51.7 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the cell membrane of cells.