Anti-TBXT antibodies are used in the immunodetection of the protein T-box transcription factor T. In humans, the canonical protein has a reported length of 435 amino acid residues and a mass of 47.4 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the testis, but not in other, normal tissues. TBXT is reported to be involved in transcriptional regulation of genes required for mesoderm formation and differentiation. The TBXT gene has been associated with the disease, Neural tube defects. Synonyms for this target antigen include T, TFT, T brachyury transcription factor, T, brachyury homolog, brachyury protein, protein T, and SAVA. TBXT gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species.