Anti-CHST9 antibodies are used in the immunodetection of the protein carbohydrate sulfotransferase 9. In humans, the canonical protein has a reported length of 443 amino acid residues and a mass of 52.1 kDa. Its subcellular localization is in the Golgi and is secreted. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in trachea. A member of the Sulfotransferase 2 protein family, CHST9 is known to catalyze the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Post-translational modifications have been described, including glycosylation.
The CHST9 marker can be used to identify Cerebral Cortex Chandelier Neurons, Hippocampal Gyrus Chandelier Neurons, Gray Matter Chandelier Neurons, and Brain Chandelier Neurons.* Synonyms for this target antigen include N-acetylgalactosamine 4-O-sulfotransferase 2, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9, galNAc-4-O-sulfotransferase 2, and GalNAc-4-sulfotransferase 2. CHST9 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4