
Get Complete Protein Characterization
Post-translational modifications, especially glycan moieties impart important functionality in your proteins that you can't simply ignore. You can analyze the carbohydrates and peptide structure by selectively applying deglycosylation strategies. Highly specific enzymatic methods permit stepwise evaluation of carbohydrate structure following cleavage from the peptide backbone. Chemical glycan removal methods enable peptide confirmation by downstream methods such as mass spectrometry. These complementary approaches provide comprehensive profiling of native glycoproteins as biomarkers and recombinant forms selected as potential biotherapeutics. Glycoprotein profiling tools are a necessary augmentation for complete proteomic evaluation.
|