Anti-Kinesin family member 7 antibodies are used for the immunodetection of the protein encoded by the KIF7 gene. In humans, the canonical protein has a reported length of 1343 amino acid residues and a mass of 150.6 kDa. Its subcellular localization is in the cell projections and cytoplasm. A member of the Kinesin protein family, it is known to be important for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms. Post-translational modifications have been described, including ubiquitination. The gene encoding this protein is implicated in Bardet-Biedl syndrome. Other names for this target antigen include kinesin-like protein KIF7 and EQYK340. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.