Description
Submit a peptide sequence and our staff at PrimmBiotech will be happy to help you with your specific R&D project whatever the field of application of your peptide you will have the full technical support of our experts.
- Quote on the specific sequence(s) of your interest will be generated with appropriate comments and/or suggestions
- Timely communications during the production process will be provided
- Prompt post-production response is available to discuss any detail of your ongoing experiments with peptides delivered by our company
PrimmBiotech custom peptide synthesis service spans a wide variety of purity levels, scales,
modifications and
labelling agents to best fit your research needs.
Actual processing time depends on the peptide sequence, length and required modifications. Every peptide is supplied with a Quality Assurance Certificate including mass spectral and HPLC analyses certifying identity and purity. All peptides are shipped lyophilized and as gross weight. Aliquotating is available on request.
Modifications
N-terminal acetylation; C-terminal amidation free of charge
Biotinylation of N-terminal end and/or side chain of any Lysine residues within a sequence
Incorporation of D-residues
Specific side chain phosphorylation of Serine, Threonine, Tyrosine residues
Specific side chain glycosylation of Serine, Threonine, Tyrosine, Asparagine residues
Acylation of N-terminal end and/or side chain of any Lysine residues within a sequence with any commercially available chemical moiety bearing a reactive carboxylic group
Incorporation of organic building blocks mimicking elements of secondary structure
Cyclization through S-S bond: (single and multiple) disulphide bridge formation
Cyclization through amide bond: tail to side-chain (N-terminus-Asp/Glu); side chain to side chain (Lys-Asp/Glu); head to tail (C-terminus/N-terminus) and head to side-chain (C-terminus/Lys) only for sequences bearing either one of Asp, Glu, Asn, Gln residues
Conjugations to carrier-proteins: KLH, OVA, BSA, …
Labelling
Of N-terminal end and/or side chain of any Lysine residues within a given sequence with any commercially available chromophore bearing a reactive carboxylic group (FAM, TAMRA etc)
Incorporation of fluorophore/quencher pairs for FRET: (FAM/DABCYL; EDANS/DABCYL; MCA/DABCYL; MCA/DNP)
Incorporation of a large variety of amino acidic residues bearing stable isotopes 2H, 13C, 15N
Incorporation within a given sequence of chelating agents (DOTA, DTPA, DTPAGlu, …) to give very stable complexes with radioactive ions such as 111-Indium, 67-Gallium, 68-Gallium,177-Lutetium, 90-Yttrium, 99m-Technetium...
Bioactive Peptide synthesis
Custom design
The Bioactive peptides are molecules of peptidic nature or origin which display a biological behaviour or activity which can be developed at the industrial level for pharmaceutical, diagnostic, chemical and agro-food applications. In this way it is possible to obtain modified peptides with superior properties for therapeutic applications. Primm offers a design strategy for developing your Bioactive peptides.