1-Pyrenesulfonyl chloride
from
AnaSpec
Description
1-Pyrenesulfonyl chloride is an UV excitable amino-reactive fluorophore that is widely used to develop ratiometric fluorescent membrane probes. In general, pyrene fluorophores have concentration-dependent fluorescence due to the formation of excimer. The excimer has long fluorescence lifetime.
References
Andreoni A, et al. (1994). Fluorochromes with long-lived fluorescence as potential labels for pulsed laser immunocytofluorometry: photophysical characterization of pyrene derivatives. J Biochem Biophys Methods 29, 157-72; Gorovits BM and Horowitz PM (1995). The molecular chaperonin cpn60 displays local flexibility that is reduced after binding with an unfolded protein. J Biol Chem 270, 13057-62.