N-(1-Pyrene)maleimide
from
AnaSpec
Description
N-(1-Pyrene)maleimide is an UV excitable thiol-reactive fluorophore that is widely used to develop ratiometric fluorescent membrane probes. In general, pyrene fluorophores have concentration-dependent fluorescence due to the formation of excimer.
References
Ohyashiki T, et al. (1989). Changes in the fluorescence characteristics of N-(1-pyrene) maleimide bound to the intestinal brush-border membranes by neuraminidase treatment. Chem Pharm Bull (Tokyo) 37, 2165-9; Sedgwick EG, et al. (1997). Cross-linking and N-(1-pyrenyl)maleimide labeling of cysteine mutants of proton-pumping pyridine nucleotide transhydrogenase of Escherichia coli. Biochemistry 36, 15285-93.