Mouse Anti- Human CD163 Monoclonal Antibody, Biotin Conjugated
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United States Biological
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Product
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Mouse Anti- Human CD163 Monoclonal Antibody, Biotin Conjugated
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Company
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United States Biological
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Price
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Pricing Info
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More Information
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View Company Product Page
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Target
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CD163
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Catalog Number
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C2548-90C
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Quantity
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250ug
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Species
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Human
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Reactivity
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Human
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Conjugate/Tag/Label
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Biotin
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Applications
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E
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Host
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Mouse
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Type
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Monoclonal Antibody
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Isotype
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IgG1
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Original Item Name
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CD163 (Hemoglobin/Haptoglobin Complex Receptor, M130 antigen, Ber-Mac3, Ki-M8, SM4) (Biotin)
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Target/Molecule Synonym
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(Hemoglobin / Haptoglobin Complex Receptor, M130 antigen, Ber-Mac3, Ki-M8, SM4)
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Description
CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes.
Applications:
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution:
ELISA: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Hybridoma:
Mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human CD163.
Storage and Stability:
Lyophilized powder may be stored at -20¡C. Stable for 12 months at -20¡C. Reconstitute with sterile PBS, sterile 40-50% glycerol, aliquot and store at -20¡C. Reconstituted product is stable for 12 months at -20¡C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.