Mouse Anti- Human CD163 Monoclonal Antibody, Unconjugated
from
United States Biological
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Product
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Mouse Anti- Human CD163 Monoclonal Antibody, Unconjugated
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Company
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United States Biological
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Price
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Pricing Info
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More Information
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View Company Product Page
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Target
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CD163
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Catalog Number
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C2548-90F
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Quantity
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250ug
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Species
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Human
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Reactivity
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Human
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Conjugate/Tag/Label
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Unconjugated
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Applications
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E FC WB
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Host
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Mouse
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Type
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Monoclonal Antibody
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Isotype
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IgG1
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Original Item Name
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CD163 (Hemoglobin/Haptoglobin Complex Receptor, M130 antigen, Ber-Mac3, Ki-M8, SM4)
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Target/Molecule Synonym
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(Hemoglobin / Haptoglobin Complex Receptor, M130 antigen, Ber-Mac3, Ki-M8, SM4)
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Description
CD163 is up-regulated on mononuclear phagocytes by IL-10, IL-6, and dexamethasone and serves as a receptor for the hemoglobin-haptoglobin complex. Lipopolysacharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant. CD163 expression is restricted to cells of monocyte lineage and increases as monocytes mature into macrophages. CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes.
Applications:
Suitable for use in Flow Cytometry, ELISA, Western Blotting. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4¡C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20¡C. Aliquots are stable for at least 12 months at -20¡C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.